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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CSNK1A1L All Species: 17.88
Human Site: T327 Identified Species: 28.1
UniProt: Q8N752 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N752 NP_660204.1 337 39086 T327 Q T Q T G K Q T E K N K N N V
Chimpanzee Pan troglodytes XP_522662 337 39019 T327 Q T Q T G K Q T E K N K N N V
Rhesus Macaque Macaca mulatta XP_001085343 337 38964 T327 Q T Q T G K Q T E K N K N N V
Dog Lupus familis XP_867638 336 38749 T327 Q T P T G K Q T D K T K S N M
Cat Felis silvestris
Mouse Mus musculus Q9JMK2 416 47304 Q406 V S R L A A S Q T S V P F D H
Rat Rattus norvegicus P97633 325 37477 Q318 S S S G Q G Q Q A Q T P T G F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P67962 337 38882 T327 Q T P T G K Q T D K S K S N M
Frog Xenopus laevis Q5BP74 415 47421 P401 R M S T S Q I P S R V T S S G
Zebra Danio Brachydanio rerio Q7T2E3 403 46225 K357 T G M E R E R K V S M R L H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P54367 337 39516 N330 D K D K E K Q N G K P L I A D
Honey Bee Apis mellifera XP_393612 350 40282 G331 A Q N A Q G Q G Q A Q G Q P P
Nematode Worm Caenorhab. elegans P42168 341 39018 S326 T Q G A T V P S A G V P A G V
Sea Urchin Strong. purpuratus XP_786391 348 40003 E341 P G T A K H S E S R S K S K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42158 450 50928 V388 S S R R V T A V S G S R D N F
Baker's Yeast Sacchar. cerevisiae P29295 494 57322 N478 V P P Q M R S N P Q Q P P Q D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 97.9 90.5 N.A. 54.5 88.1 N.A. N.A. 90.5 53.9 56.5 N.A. 70.6 76.2 75.3 74.1
Protein Similarity: 100 99.6 99.4 94.3 N.A. 66.1 91 N.A. N.A. 94.6 66 68.2 N.A. 81.3 84 82.1 84.2
P-Site Identity: 100 100 100 66.6 N.A. 0 6.6 N.A. N.A. 66.6 6.6 0 N.A. 20 6.6 6.6 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 20 20 N.A. N.A. 93.3 40 26.6 N.A. 20 13.3 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. 48.6 39.8 N.A.
Protein Similarity: N.A. N.A. N.A. 61.7 52.8 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 20 7 7 7 0 14 7 0 0 7 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 0 14 0 0 0 7 7 14 % D
% Glu: 0 0 0 7 7 7 0 7 20 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 14 % F
% Gly: 0 14 7 7 34 14 0 7 7 14 0 7 0 14 7 % G
% His: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 7 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 7 0 0 % I
% Lys: 0 7 0 7 7 40 0 7 0 40 0 40 0 7 0 % K
% Leu: 0 0 0 7 0 0 0 0 0 0 0 7 7 0 0 % L
% Met: 0 7 7 0 7 0 0 0 0 0 7 0 0 0 14 % M
% Asn: 0 0 7 0 0 0 0 14 0 0 20 0 20 40 0 % N
% Pro: 7 7 20 0 0 0 7 7 7 0 7 27 7 7 7 % P
% Gln: 34 14 20 7 14 7 54 14 7 14 14 0 7 7 0 % Q
% Arg: 7 0 14 7 7 7 7 0 0 14 0 14 0 0 14 % R
% Ser: 14 20 14 0 7 0 20 7 20 14 20 0 27 7 0 % S
% Thr: 14 34 7 40 7 7 0 34 7 0 14 7 7 0 0 % T
% Val: 14 0 0 0 7 7 0 7 7 0 20 0 0 0 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _